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KMID : 1134120060090020145
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Journal of Breast Cancer
2006 Volume.9 No. 2 p.145 ~ p.150
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A Case-Control Study on the Risk Factors of Breast Cancer in Korean Women
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Yi Mi-Suk
Youn Hyun-Jo
Jung Sung-Hoo
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Abstract
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Purpose: The annual incidence of breast neoplasms continues to rise, but only a few studies on the risk factors for breast neoplasms in Korea have been conducted. The aim of this study was to analyze the risk factors of breast neoplasms in Korean women using a case-control study.
Methods: The participants in the study were 131 women diagnosed with breast neoplasms at the Department of Surgery, Chonbuk National University Hospital between April 1999 and March 2002. Individually age matched cases were used as the control group. A conditional logistic regression analysis was used to estimate the odds ratio (OR) and 95% confidence interval (95% CI).
Results: The mean age of the patients was 45.0 years, with 50.38% between 40 and 49 years. After adjustment for potential confounders, a positive family history of breast cancer and breast pain were associated with an increased risk of breast neoplasms (OR=4.916, 95% CI=1.055~22.913; OR=4.308, 95% CI=2.179~8.514). A regular breast examination was associated with breast neoplasms incidience (OR=3.543, 95% CI=1.860~6.751). However, other factors including reproductive factors, were found to exhibit no significant association with breast neoplasms.
Conclusion: The present study suggests a family history of breast neoplasms, breast pain and a regular breast examination was associated with breast neoplasms incidence in Korean women. (J Breast Cancer 2006;9:145-150)
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KEYWORD
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Breast neoplasms, Risk factors, Case-control studies
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